necrosis = cell death
causes:
- lack of blood supply
- heat / cold
- traumatic effects
- bacterial toxins
- endogenous enzymes
- autoimmune reaction
first Coagulation necrosis
strong protein coagulation, the cytoplasm becomes solid, opaque, compact and white. Architecture of the tissue remains shadowy. The sites look conical. occurrence mainly heart, liver, kidney and spleen.
inflammation of the pancreas with cell death, necrotizing pancreatitis
second caseous necrosis
Struckturlose necrosis with complete loss of the original tissue architecture, dull white appearance. consistency: white dry, brittle and greasy. occurrence mainly from pulmonary tuberculosis, syphilis, and fungal infections.
lung (tuberculosis) third Colliquation
Gewebsverflüssigungen This leads to the central nervous system.
4th moist gangrene
Occurs on extremities and internal organs as a result of arterial occlusion with subsequent colonization by rotting bacteria. It comes to smelly urine degeneration of the tissue. (Such as smoker's leg)
5th dry gangrene
case of significant water loss occurs blackish discoloration, shrinkage, and mummy-like appearance in extremities.
Is necrotic tissue which has not been absorbed. -> Kalkkörnchen in the tissue.
consequences:
- leukocyte infiltration
- Demakation (differentiation between health and sickness)
- rejection of necrotic tissue
- leaving an ulcer
- scarring
- formation of cavities (caverns)
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