antibiotics means "acting against something alive."
- are of course originally formed metabolites of fungi and bacteria
- today are predominantly synthetic or semi-synthetic antibiotics used
effect - bacteriostatic = inhibit growth and / or multiplication of bacteria
- bactericidal (bacteriolytic) = bacteria are killed
Antibiotics - Therapy Indications: - bacterial infections
- prophylactic antibiotics - treatment for ...
- contamination-risk surgery
- diagnostic / therapeutic interventions for heart valve insufficiency (& artificial heart valves)
distinction: broad-spectrum-A. | narrow band-A. |
- cover a broad excitation field
- high hit probability for unknown pathogens
- corresponds to the clinical reality
| - cover a narrow excitation field
- very effective action
- avoid disturbance of the physiological microflora
- possible after the detection of pathogens ( antibiogram) and resistance testing
|
forms of antibiotics - treatment monotherapy | combination therapy |
| - broad antibiotic coverage, for unknown pathogens or mixed infections
- to prevent development of resistance
|
side effects most common side effects | patient observation |
allergies | lesions, redness, pustules, itching |
gastrointestinal intolerance | excretion, nausea, vomiting, diarrhea |
damage to the physiological resident flora in the intestine, skin, mucous membranes, female genital | itching, vaginal discharge |
resistance | stop the symptoms of the underlying disease |
vein irritation from iv administration | puncture of the venous access; Scmerzen |
nursing principles - keeping accurate dosing / dosing intervals
- when taken orally, gastrointestinal complaints, the absorption decrease of the antibiotic -> the therapy is ineffective
- close attention to the preparation requirements (with iv administration)
- Consistent intake to the end
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