ì Synonyms: CHD = coronary artery disease ischemic coronary artery disease
ì Definition: manifestation of atherosclerosis in the coronary arteries.
ì process:
-
Atherosclerosis in the coronary arteries -
development of stenosis -
reduced blood flow to the heart muscle -
mismatch between 0 2 -demand and O 2 offer
ì Etiology: [ á increased =]
risk factors of first order 2 risk factors = heart attack risk increased 4-fold 3 risk factors = risk of heart attack 10-fold increase | risk factors of second order |
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ì pathophysiology (4 degrees of severity of coronary stenosis)
Grade 1 25 - 49%
; Grade 2 50 - 74% Grade 3 75
- 99% (critical stenosis)
, Grade 4 100% (total occlusion)
Ü only 75% the first symptoms
two forms of CHD
latent coronary heart disease ~ KHK manifest
(asymptomatic (Symptomatische DL)
DL; Stumme ;
Ischämie)
diseases manifest CHD
diseases | share of onset (in%) | Description |
angina pectoris | 55 | chest pain due to reversible Myocardischmie |
heart attack | 25 | Ischemic Myocardnekrose |
heart failure | - | Ischemic heart muscle damage |
arrhythmias | - | ventricular arrhythmias and ventricular fibrillation |
Sudden cardiac death | 20 |
ì coronary vessels (coronary arteries)
Extras:
# are end arteries
#, there are no anastomoses with the einzellne arteries
# dies at closing tissue from
effect of the risk factor nicotine
adrenal medulla:
-
release of adrenaline and noradrenaline -
ð peripheral increase in heart rate -
ð increase in O 2 -consumption of the heart
coronary vessels & Vessels:
-
narrowing of these vessels -
ð increased vascular resistance -
ð reduced O 2 offer
vessel walls:
-
promote platelet aggregation -
increase in fibrinogen levels -
damage the intima of the arteries -
ð increase the clotting ability Blood -
ð encouraging early deposits -
ð promote atherosclerosis
effect of the risk factor of alcohol
positive | negative reduced |
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main complaints / symptoms in diseases of the heart
symptom | statement | differential diagnosis |
chest pain | linksthorakal or retrosternal | angina pectoris, pulmonary embolism, heart attack, tuberculosis |
dyspnea | breathlessness | pneumonia, lung CA, heart attack, Tbc |
palpitations | unpleasant perception of one's own heartbeat | heart attack, hyperthyroidism |
cyanosis | bluish discoloration of lips, mucous membranes, skin | hypothermia, pulmonary embolism |
distended neck veins | by damming the blood before the right heart | bronchial CA, pericarditis, valve stenosis |
nocturia | increased urination at night | right heart failure, urinary incontinence |
cough | - | flu, colds, pneumonia |
syncope | sudden, brief loss of consciousness, by reducing supply to the brain with O 2 | cardiac arrhythmias, arteriosclerosis |
reduced exercise capacity | - | - |
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