ì   Synonyms:  CHD = coronary artery disease ischemic coronary artery disease   
   ì   Definition:  manifestation of atherosclerosis in the coronary arteries. 
   ì   process:  
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Atherosclerosis in the coronary arteries -  
development of stenosis -  
reduced blood flow to the heart muscle -  
mismatch between 0 2 -demand and O 2 offer 
  ì   Etiology:  [ á  increased =] 
 |   risk factors of first order 2 risk factors = heart attack risk increased 4-fold 3 risk factors = risk of heart attack 10-fold increase  |  risk factors of second order | 
 
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  ì   pathophysiology  (4 degrees of severity of coronary stenosis) 
  Grade 1 25 - 49% 
  ; Grade 2 50 - 74% Grade 3 75 
  - 99% (critical stenosis) 
  , Grade 4 100% (total occlusion) 
   
   Ü   only 75% the first symptoms  
  two forms of CHD 
   latent coronary heart disease ~ KHK manifest  
  (asymptomatic (Symptomatische DL) 
  DL; Stumme ; 
  Ischämie)  
                                                     
 
  diseases manifest CHD 
   
 | diseases | share of onset (in%) | Description | 
| angina pectoris |   55  |  chest pain due to reversible Myocardischmie | 
| heart attack |   25  |  Ischemic Myocardnekrose | 
| heart failure |   -  |    Ischemic heart muscle damage  |  
| arrhythmias |   -  |  ventricular arrhythmias and ventricular fibrillation | 
| Sudden cardiac death |   20  |  
  ì  coronary vessels (coronary arteries) 
  Extras: 
  # are end arteries 
  #, there are no anastomoses with the einzellne arteries 
  # dies at closing tissue from 
   effect of the risk factor nicotine  
  adrenal medulla: 
 -  
release of adrenaline and noradrenaline -  
ð peripheral increase in heart rate -  
ð increase in O 2 -consumption of the heart 
 coronary vessels & Vessels: 
 -  
narrowing of these vessels -  
ð increased vascular resistance -  
ð reduced O 2 offer 
 vessel walls: 
 -  
promote platelet aggregation -  
increase in fibrinogen levels -  
damage the intima of the arteries -  
ð increase the clotting ability Blood -  
ð encouraging early deposits -  
ð promote atherosclerosis 
  effect of the risk factor of alcohol  
 | positive | negative reduced | 
 
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  main complaints / symptoms in diseases of the heart  
 | symptom | statement | differential diagnosis | 
| chest pain | linksthorakal or retrosternal | angina pectoris, pulmonary embolism, heart attack, tuberculosis | 
| dyspnea | breathlessness | pneumonia, lung CA, heart attack, Tbc | 
| palpitations | unpleasant perception of one's own heartbeat | heart attack, hyperthyroidism | 
| cyanosis | bluish discoloration of lips, mucous membranes, skin | hypothermia, pulmonary embolism | 
| distended neck veins | by damming the blood before the right heart | bronchial CA, pericarditis, valve stenosis | 
| nocturia | increased urination at night | right heart failure, urinary incontinence | 
| cough |   -  |  flu, colds, pneumonia | 
| syncope | sudden, brief loss of consciousness, by reducing supply to the brain with O 2 | cardiac arrhythmias, arteriosclerosis | 
| reduced exercise capacity |   -  |    -  |  
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